Development of Nanomedicine from Copper Mine Tailing Waste: A Pavement towards Circular Economy with Advanced Redox Nanotechnology
نویسندگان
چکیده
Copper, the essential element required for human body is well-known its profound antibacterial properties, yet salts and oxides of copper metals in mine tailings are reported to be a big burden modern era. Among other oxides, CuO, particular, known have beneficial effects on humans, while slight nanoengineering viz., surface functionalization nanometer-sized oxide shown make some paradigm shift using inherent redox property. Here, we synthesized CuO nanoparticles functionalized it with citrate ligand an enhanced property better solubility water. For structural analysis nanohybrid, standard analytical tools, such as electron microscopy, dynamic light scattering, X-ray diffraction studies were conducted. Moreover, FTIR UV-VIS spectroscopy performed confirm functionalization. The study results, against model bacteria (S. hominis), show that nanohybrids provide favorable outcomes antibiotic-resistant organisms. suitability nanohybrid use photodynamic therapy was also confirmed, under activity increased substantially. antibiotics further supported by computational biology, which reconfirmed outcome our experimental studies. We extracted nanogranules (top-down technique) from two places, each different geographical locations, them ligands order characterize similar functional properties obtained nanoparticles, bottom-up technique. observed offers compared those provides avenue circular economy utilization waste into nanomedicine, best mankind.
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ژورنال
عنوان ژورنال: Catalysts
سال: 2023
ISSN: ['2073-4344']
DOI: https://doi.org/10.3390/catal13020369